KEGG   Homo sapiens (human): 112817
Entry
112817            CDS       T01001                                 
Symbol
HOGA1, C10orf65, DHDPS2, DHDPSL, HP3, NPL2
Name
(RefSeq) 4-hydroxy-2-oxoglutarate aldolase 1
  KO
K18123  4-hydroxy-2-oxoglutarate aldolase [EC:4.1.3.16]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00330  Arginine and proline metabolism
hsa00630  Glyoxylate and dicarboxylate metabolism
hsa01100  Metabolic pathways
Disease
H00117  Primary hyperoxaluria
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    112817 (HOGA1)
  09105 Amino acid metabolism
   00330 Arginine and proline metabolism
    112817 (HOGA1)
Enzymes [BR:hsa01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.3  Oxo-acid-lyases
    4.1.3.16  4-hydroxy-2-oxoglutarate aldolase
     112817 (HOGA1)
SSDB
Motif
Pfam: DHDPS
Other DBs
NCBI-GeneID: 112817
NCBI-ProteinID: NP_612422
OMIM: 613597
HGNC: 25155
Ensembl: ENSG00000241935
UniProt: Q86XE5
Structure
Position
10:97584389..97612802
AA seq 327 aa
MLGPQVWSSVRQGLSRSLSRNVGVWASGEGKKVDIAGIYPPVTTPFTATAEVDYGKLEEN
LHKLGTFPFRGFVVQGSNGEFPFLTSSERLEVVSRVRQAMPKNRLLLAGSGCESTQATVE
MTVSMAQVGADAAMVVTPCYYRGRMSSAALIHHYTKVADLSPIPVVLYSVPANTGLDLPV
DAVVTLSQHPNIVGMKDSGGDVTRIGLIVHKTRKQDFQVLAGSAGFLMASYALGAVGGVC
ALANVLGAQVCQLERLCCTGQWEDAQKLQHRLIEPNAAVTRRFGIPGLKKIMDWFGYYGG
PCRAPLQELSPAEEEALRMDFTSNGWL
NT seq 984 nt   +upstreamnt  +downstreamnt
atgctgggtccccaagtctggtcttctgtgaggcaggggctaagcaggagcttgtccagg
aatgtgggggtctgggcctcaggggaggggaagaaggtggacattgcgggtatctacccc
cctgtgaccacccccttcactgccactgcagaggtggactatgggaaactggaggagaat
ctgcacaaactgggcaccttccccttccgaggcttcgtggtccagggctccaatggcgag
tttcctttcctgaccagcagtgagcgcctcgaggtggtgagccgtgtgcgccaggccatg
cccaagaacaggctcctgctagctggctccggatgcgagtccactcaagccacagtggag
atgaccgtcagcatggcccaggtcggggctgacgcggccatggtggtgaccccttgctac
tatcgtggccgcatgagcagtgcggccctcattcaccactacaccaaggttgctgatctc
tctccaatccctgtggtgctgtacagtgtcccagccaacacagggctggacctgcctgtg
gatgcagtggtcacgctttcccagcacccgaatattgtgggcatgaaggacagcggtggt
gatgtgaccaggattgggctgattgttcacaagaccaggaagcaggattttcaggtgttg
gctggatcggctggctttctgatggccagctatgccttgggagctgtggggggcgtctgc
gccctggccaatgtcctgggggctcaggtgtgccagctggagcgactgtgctgcacgggg
caatgggaagatgcccagaaactgcagcaccgcctcattgagccaaacgctgcggtgacc
cggcgctttgggatcccagggctgaagaaaatcatggactggtttggctactatggaggc
ccctgccgcgcccccttgcaggagctgagccccgctgaggaggaggcactgcgcatggat
ttcaccagcaacggctggctctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (12)   
   RefSeq(nuc) (2)   
   GenBank (5)   
   EMBL (5)   
3D Structure (2)   
   PDB (2)   
Protein domain (1)   
   Pfam (1)   
All databases (45)   

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